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Gestational diabetes: A diabetes predictor in fathers

Gestational diabetes, a type of diabetes that occurs during pregnancy, affects between three and 20 per cent of pregnant women. Those who develop gestational diabetes are 7 times as likely to eventually develop type 2 diabetes in the years following pregnancy.

In a large study analyzing 20 years of data from Quebec, a team from the Research Institute of the 捆绑SM社区 Health Centre (RI-MUHC) has demonstrated that gestational diabetes signals future diabetes risk not only in mothers, but also in fathers. The study was recently published in Diabetes Care.

Published: 13 August 2015

鈥淲e observed that the incident of diabetes was 33% greater in men whose partner has gestational diabetes compared with men whose partners did not have gestational diabetes,鈥 says the lead author of the study, Dr. Kaberi Dasgupta, endocrinologist at the MUHC and an associate professor of Medicine at 捆绑SM社区. 鈥淭his is the first study to demonstrate a link between in mothers and diabetes incidence in fathers.鈥

Prior studies have shown partners to be similar in their weight and physical activity. Moreover, Dr. Dasgupta鈥檚 team has shown evidence in a that spousal diabetes was a diabetes risk factor. Then the researchers hypothesized that gestational diabetes in mothers signals a possible diabetes incidence in fathers.听 Gestational diabetes occurs when couples are in young to middle adulthood. Diabetes risk factors in these years are of high importance as they offer an opportunity for long term prevention.

The researchers randomly selected singleton live births from 1990 to 2007 with a positive diagnosis for gestational diabetes in mothers and matched controls without gestational diabetes from health administrative, birth and death registry data from the province of Quebec.听 Then, they identified fathers with type 2 diabetes from the time of the mother鈥檚 post-delivery discharge from the hospital to the father鈥檚 departure from Quebec, death or end of the study period (March 31, 2012). Overall, 70,890 fathers were evaluated (half with partners with gestational diabetes).

听鈥淥ur analysis suggests that couples share risk partly because of their shared social and cultural environment, which may contribute to health behaviours and attitudes,鈥 explains Dr. Dasgupta. 鈥淭he study reinforces the findings of our previous study on shared risk for diabetes in spouses and prior studies indicating that less healthy eating habits and low physical activity could be shared within a household. Our data suggest that gestational diabetes could be leveraged as a tool to enhance diabetes detection and prevention in fathers.鈥欌

About the study听

This work was supported by the . Dr. Dasgupta听 holds the Fonds de recherche du Qu茅bec 鈥 Sant茅 (FRQS) Senior Clinician-Scientist Award.

The article (Observation Letter) entitled was coauthored by Kaberi Dasgupta, Deborah Da Costa, Elham Rahme (Research Institute of the 捆绑SM社区 Health Centre; Department of Medicine, 捆绑SM社区); Nancy Ross (Department of Geography, 捆绑SM社区);听 Sara Meltzer (Department of Medicine, 捆绑SM社区); Meranda Nakhla (Research Institute of the 捆绑SM社区 Health Centre; Department of Pediatrics, 捆绑SM社区); and Youssef Habel (Research Institute of the 捆绑SM社区 Health Centre).

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