Killam Seminar Series: Aging Mechanisms and Progressive Multiple Sclerosis
Supported by the generosity of the Killam Trusts, The Neuro's Killam Seminar Series invites outstanding guest speakers whose research is of interest to the scientific community at The Neuro and 捆绑SM社区.
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Shalina Sheryl Ousman
Associate Professor, Department of Psychiatry and Neurosicence, Universit茅 Laval
Host:听alyson.fournier [at] mcgill.ca (Alyson Fournier)
Abstract:听Despite the availability of over twenty disease modifying therapies for relapsing-remitting multiple sclerosis, most people with multiple sclerosis (MS) still progress to a devastatingly disabling form called progressive MS. The scarcity of medications for progressive MS is due to our lack of understanding of the underlying mechanisms and etiologic triggers that cause axonal loss and demyelination that drive the progression of disability. Because age is the only factor to date that correlates with progression in MS, my lab is investigating if mechanisms of aging such as the gut microbiota and autophagy are etiologic triggers that contribute to neuroinflammatory and neurodegenerative pathologies that drive MS progression.
