捆绑SM社区

Dr. April Rose

Academic title(s): 

Associate Member - Department of Medicine

Assistant Professor - Department of Oncology

Dr. April Rose
Contact Information
Address: 

Lady Davis Institute for Medical Research
Jewish General Hospital
3755 C么te Ste-Catherine Road,
Montreal, Qc, H3T 1E2

Phone: 
(514) 340-8222 ext. 27343
Email address: 
april.rose [at] mcgill.ca
Current research: 

Dr. April Rose is a clinician scientist and Assistant Professor within the Department of Oncology at 捆绑SM社区. She is a staff Medical Oncologist at the Segal Cancer Centre of the Jewish General Hospital (CIUSSS West-Central Montreal) and a Principal Investigator at the Lady Davis Institute for Medical Research. Dr. Rose has clinical interests in melanoma and genitourinary cancers. Her research interests are in molecular and translational oncology as well as in the development of novel immunogenomic therapies for treatment resistant cancers.

Major Research Activities

A) Evaluating molecular mechanisms of therapeutic resistance in tumors with MAPK pathway mutations

B) Assessing the impact of the metastatic bone tumor microenvironment on anti-cancer therapeutic responsiveness

C) Minimally Invasive Precision Medicine for patients with Metastatic Cancer

Projects: 

1.Characterizing mechanisms of immunotherapy resistance in NRAS mutant melanoma.

2. Developing novel treatment strategies to overcome MAPK inhibitor resistance in tumors with non-V600 BRAF mutations.

3. Defining mechanisms of immunotherapy response and resistance in bone metastatic cancer.

Selected publications: 

Research areas: 
Bone/Adipose tissues
Cancer
Drug discovery/ Therapeutics
Epidemiology
Fundamental Research
Immunology
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