CCVC Seminar: Dr. Huw M. L. Davies - Collaborative Approach for C-H Functionalization

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CCVC Seminar: Dr. Huw M. L. Davies - Collaborative Approach for C-H Functionalization

Tuesday, October 13, 2015 13:00to14:30

Maass Chemistry Building Room 10, 801 rue Sherbrooke Ouest, Montreal, QC, H3A 0B8, CA

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The development of practical methods for site selective C-H functionalization is of intense current interest. This presentation will describe a collaborative approach towards achieving new C-H functionalization strategies and our recent advances in the C-H insertion chemistry of donor/acceptor-substituted carbenoids. A series of chiral dirhodium catalysts have been developed for this chemistry and they are capable of controlling which C-H bond is functionalized.聽 The application of these new synthetic strategies to the synthesis of natural products and pharmaceutical targets will be described.m

Dr.Huw M. L. Davies

Asa Griggs Candler Professor of Chemistry, Department of Chemistry, Emory University The development of practical methods for site selective C-H functionalization is of intense current interest. This presentation will describe a collaborative approach towards achieving new C-H functionalization strategies and our recent advances in the C-H insertion chemistry of donor/acceptor-substituted carbenoids. A series of chiral dirhodium catalysts have been developed for this chemistry and they are capable of controlling which C-H bond is functionalized.